Jonah Lomu, Andy Powell and Deiniol Jones all return to side, whilst Xavier Rush is rested and Craig Morgan moved to the bench. A positional change sees Kort Schubert moving to the back row in place of Maama Molitika.
"I have kept myself to myself since Christmas and have concentrated on getting back some of the strength and speed that I lost," Lomu told BBC Sport. "I wasn't in great shape when I arrived because I had been away from the game for the best part of three years.
"I had shot up in weight and was struggling with my fitness. But the guys have been great. I have trained with them every day, but I have also spent hours training on my own.
"It has been really frustrating in recent weeks because the game seems to have shut down since the start of the RBS Six Nations Championship. But I have now lost between 10 and 11 kilos which means I can get back on the serious weights and start working my way back to where I once was."
Team: Rhys Williams (c), Jonah Lomu, Jamie Robinson, Marc Stcherbina, Chris Czekaj, Nick Robinson, Mike Phillips, Andy Powell, Martyn Williams, Kort Schubert, Rob Sidoli, Deiniol Jones, Gethin Jenkins, Duane Goodfield, John Yapp
Replacements: Martin Jones / Scott Roberts, T Rhys Thomas, Chris Dicomidis, Robin Sowden-Taylor, Ryan Powell, Nick Macleod, Craig Morgan