Ruddock goes into the match without first-choice midfield pairing Gavin Henson (groin) and Tom Shanklin (knee), while leading contender Sonny Parker is battling a hamstring injury. The Blues' Jamie Robinson is still finding his feet after a year out with a knee injury and the Dragons' Hal Luscombe is out of the equation after breaking a thumb against Edinburgh on Friday night.
Ruddock has the choice of the Dragons' Ceri Sweeney in the No. 12 jersey, while veteran Mark Taylor may earn a recall if Parker fails next week's fitness test. Skipper Gareth Thomas played at outside centre for Toulouse on Saturday and may move from fullback to fill the problem area.
World-class prop Gethin Jenkins (shoulder) will also miss the autumn Test series, while doubts linger over Lions star Ryan Jones after he injured a shoulder against Bath a week ago. Ironically, the man in the Bath No. 8 jersey that day is being tipped as Jones's replacement in the Wales lineup.
Gareth Delve has been tipped as a Wales star for several years, but a serious shoulder injury meant his 2003 match against the Barbarians is his only match in the red jersey. But after an eye-catching performance in Bath's Powergen Cup victory over the Ospreys, his name is back in the headlines.
"I got a text from Scott Johnson after the Ospreys game, asking if Gareth was available for Wales squad training," Bath coach John Connolly said. "Gareth is a big, strong man. He's incredibly athletic, he's a massive ball-carrier, a good defender and he has the physicality for Test rugby.
"I think Gareth will be involved in the autumn. Ryan Jones is a good player, but he took another knock against us so you don't know. And Colin Charvis is competing with Gareth - I think Charvis is an openside flanker. I think you'll see Gareth in the 22 for the autumn Tests."
Connolly said the most exciting thing about Delve was that he still had a lot of improvement in him after his horror run of injuries.
"Gareth is definitely on an upward spiral - he didn't play for three years and it's always going to take a year to come back into it," the Australian said. "He came into some form slowly last year and he's really stepping up to the mark this season. Against the Ospreys, he was the best backrower, and the best thing is that you know he has a lot of improvement in him."
Wales Under 18 captain Callum Bradbury is delighted to have seen his side claim a narrow 18-17 victory against a strong SA Schools 'A' side to end the three-match Under 19 International Series in South Africa on a high note.
The Wales U18 squad spent an emotional day in the drug-riddled townnship of Hout Bay. Hout Bay Warriors President Fred Johannes said the visit was 'the talk of the town' and will dream about the day everyday for the rest of his life.
RGC 1404's new head coach Mark Jones is hoping to build 'something special' in north Wales and is already looking forward to the development region participating in the Principality Premiership for the very first time.
A joint venture between the WRU and Admiral saw hundreds of children enjoy the Admiral Festival of Rugby held at the National Centre of Excellence at the weekend where Welsh internationals Sam Warburton, Scott Williams and Rob Evans were in attendance.
Wll Jones leads Wales U18s into battle this afternoon against Italy where the Welsh side will be seeking to bounce back from their narrow defeat to SA Schools in their opening clash of the U19 International Series
All four regions attended a successful training camp staged last weekend at the WRU National Centre of Excellence. It was a chance for new Wales Women's head coach Rowland Phillips to deliver his key messages to players and coaches as he prepares for the new season.
Wales U18 Team Manager Gethin Watts believes the next couple of weeks will be 'extremely beneficial' to the future of Welsh rugby as his side prepare to take part in the Under 19 International Series being staged in South Africa.
The WRU is searching for 12 new rugby development apprentices following a successful first year of its WRU Coach Core programme. Craig Duncan and Jess Hancock have flourished in the first year of the programme which has given them a real direction in their lives.
The WRU signed TV comedian Rhod Gilbert up to a 'Coaching Children Level 1' course before letting him loose on an U8s side at Whitland Junior Borderers - we went behind the scenes to film the making of 'Rhod Gilbert's Work Experience' see the results here.
Llandovery are aiming to make it three titles in a row in this year's Foster's National 7s being held at BT Sport Cardiff Arms Park on Sunday 28 August. Drovers assistant coach Simon Davies and Lee Rees assess their sides chances
A pioneering strength and conditioning programme has been delivered to more than 8000 boys and girls at hub schools throughout Wales this season, helping to develop stronger, more flexible athletes for rugby and other sports.
The Singha Premiership Rugby 7s Series returns to the BT Sport Cardiff Arms Park on July 22nd when all four Welsh regions go head to head. Scarlets skills coach Dai Flanagan and Blues Elite Performance Pathway Manager Richard Hodges along with current Welsh squad members were at the launch of this season's event