Clermont Auvergne's medical staff had been tipping that Jones would make a stunning recovery from an ankle injury suffered against Biarritz last weekend. He was included in the initial squad of 24 named to play Stade Francais Paris on Saturday, but didn't make the final cut.
'It's a pity I couldn't play, because we've got an incredible crowd in, the weather's perfect and these are the sorts of games everyone wants to play,' Jones said. 'I believe I could have played, but there are still a few doubts about the ankle. The only wish you have when you're injured is to get back playing as quickly as possible.
'I really thought I would be fit for this game, but it's obviously going to take a few more days.'
A Clermont club spokesman said Jones's ankle would be looked at on Wednesday, in the hope of playing him against Castres next weekend. The delay in his return is another setback for Wales coach Ruddock, who is spending more time looking at X-rays than training videos these days.
World-class prop Gethin Jenkins (shoulder) and gifted centre Gavin Henson (groin) have already been ruled out of the autumn internationals. Scrum-half Dwayne Peel will have an ankle operation on Monday and will out of action for at least a fortnight, although understudy Gareth Cooper started on the bench for the Dragons on Saturday night.
Centre Tom Shanklin (knee) came through the Blues' loss to Wasps on Friday night unscathed, while Lions backrower Ryan Jones (shoulder) returns for the Ospreys against Bath on Sunday.
Ruddock's biggest problem next month could be at hooker. Robin McBryde has retired from rugby because of on-going neck problems, while possible replacements Rhys Thomas, Matthew Rees and Gareth Williams are all twiddling their thumbs on the injury list.
On the good-news front, Scarlets backrower Dafydd Jones (finger) is making a faster-than-expected recovery and may be available for the autumn Tests, and captain Gareth Thomas's sore shoulder is not considered a problem.
WRU International Skills Coach Jason Strange is a busy man, combining the new role with that of Wales Under 20 attack coach, Ebbw Vale head coach and continuing to teach at Ebbw Fawr Learning Community.
Warren Gatland and Sam Warburton look ahead to this week's crunch RBS 6 Nations tie against France, where the Wales skipper in particular is keen to make his mark, as Paris has proved a bleak place for him in the past.
Following their historic win over England, Wales Under 20 suffered a narrow, 36-34 loss to their Scottish counterparts last weekend, despite outscoring them by five tries to three. Watch the match highlights and reaction.
WRU TV go behind the scenes with the Wales squad as they put the final touches in place ahead of the clash against Scotland at Murrayfield. Follow the squad on their captain's run, the kickers visit to Murrayfield and Neil Jenkins' press conference