It should be interesting to see if Bedwas can take a quick double or whether the Sardis Road supporters can pull Ponty through.
Leaders Neath go to Pontypool mindful of a beating there at the end of last season. Another such result would be harmful to title hopes as Newport are on a roll, though they will have to contend with a lively Carmarthen Quins side, who have centre Emyr Jones on 99 career league tries. Newport need three tries for 1,000 in league rugby.
Caerphilly are still fighting to avoid relegation and if they can beat Llandovery, they will have a very faint chance, while relegated Newbridge are not playing and Llanharan, also doomed, are at Ebbw Vale.
Swansea against Bridgend is sure to bring a host of points at St Helen's and Aberavon would like to defeat Cross Keys a week before a semi-final cup appearance.
Beating Merthyr has boosted Carmarthen Quins hopes of reaching a top eight spot in the Principality Premiership. Quins captain Haydn Pugh is delighted with his team's progress and is determined that everyone from the Under 6s through to the senior team, enjoys the ride.
When the Wales squad were asked to nominate individuals who played a big part in their early playing days, Wales and Dragons full back and wing Hallam Amos thought of his former Monmouth School rugby coach John Bevan.
Sam Cross and Luke Treharne have been named as co-captains of the Wales Sevens side as head coach Gareth Williams names his 12-man squad to play in the first leg of the HSBC World Series in Dubai next weekend.
Bedwas head coach Steve Law and players Nicky Griffiths and Alun Rees extol the virtues of the close knit club as they prepare to host third place RGC 1404 - who are one place head of them on the Principality Premiership points table - on Saturday.
Many of the Wales squad have said Diolch (thank you) to someone who played an important part in their early playing days by nominating them to be invited to the Wales v South Africa match. One person, Gowerton Comprehensive geography teacher Mr Dean Mason was nominated by two of his former pupils, Dan Biggar and Sam Davies.
The second WRU disability rugby pilot has been delivered, this time in Caerphilly schools, culminating in a festival at the Caerphilly Centre of Sporting Excellence, Ystrad Mynach tomorrow. Plans are in place to set up a Disability Rugby Club in Newbridge to provide long-term playing opportunities.
WRU TV: Hear from inside the Wales camp as Neil Jenkins discusses this weekend's clash with South Africa and how the squad are looking to put in a strong performance to round of the 2016 Under Armour Series