The leaders took a while to get into their stride, then raced clear by scoring six tries with fly half Mark David gaining a try, five conversions and a penalty goal, while skipper Karl Hocking notched his 116th league try.
The Old Parish also ran in tries by flanker Marcus Sainsbury, wing Gareth John, centre Alun Brown and wing Gareth Holmes, while fly half and skipper Stuart Morris placed three penalty goals for the Athletic in a game well controlled by Clayton Thomas.
Glamorgan Wanderers remained in third place despite beating UWIC 36-12, but are now just one point behind Llangennech with a game still in hand and a better try-count.
No 8 Emyr Christopher had an outstanding game and he, Mark Heywood, Dave Willey, Lee Mullane and replacement scrum half Gareth Spain went over with Heywood converting one and landing two penalties and Jason Pocock also placed a penalty.
The students ran in tries by Rhys Edwards and Gareth Dacey and Phil Dolman converted one.
Blackwood battled their way to a 25- home win over Builth Wells and went out of therelgation zone, moving over Fleur de Lys, Carmarthen Athletic and UWIC in the process.
Fly half Jeremy Lloyd led the way with a penalty, drop goal and two conversions and tries came from Jamie Sims (2) and Christian Perry, while Rob Lloyd placed a lone penalty for Builth Wells.
Bonymaen jumped from seveth to fifth place after a 30-0 win over Tonmawr, who now are staring relegation in the face and have eight game to survive, but are already 13 points away from safety.
Scrum half Gareth James, formerly of Penygraig, notched four of the five tries by the Parc Mawr club and wing Chris Griffiths also crossed with Anthony Evans placing a penalty and conversion.
As the countdown continues for RWC2015, Tournament Chief Executive Debbie Jevans visited the Millennium Stadium to discuss preparations for the eight matches and reveal the positive news that 100,000 tickets for games at the home of Welsh rugby have sold in the last seven days.
Jason Harries is targeting a first win on the World Series circuit this season with Wales. The series returns to action this weekend in Dubai where Harries is part of a team hoping to build from its efforts in round one in October.
Wales skipper Jevon Groves says his side have addressed a few points from Gold Coast and aim to 'hit the ground running' in the next two rounds of the World Series, kicking off with this weekend in Dubai before heading off to South Africa next week.
Wales Sevens manager Steff Thomas is hopeful his side can build from a quarter-final spot in the opening round of the World Series in Australia when his side take part in the forthcoming double header in Dubai and South Africa.