The leaders took a while to get into their stride, then raced clear by scoring six tries with fly half Mark David gaining a try, five conversions and a penalty goal, while skipper Karl Hocking notched his 116th league try.
The Old Parish also ran in tries by flanker Marcus Sainsbury, wing Gareth John, centre Alun Brown and wing Gareth Holmes, while fly half and skipper Stuart Morris placed three penalty goals for the Athletic in a game well controlled by Clayton Thomas.
Glamorgan Wanderers remained in third place despite beating UWIC 36-12, but are now just one point behind Llangennech with a game still in hand and a better try-count.
No 8 Emyr Christopher had an outstanding game and he, Mark Heywood, Dave Willey, Lee Mullane and replacement scrum half Gareth Spain went over with Heywood converting one and landing two penalties and Jason Pocock also placed a penalty.
The students ran in tries by Rhys Edwards and Gareth Dacey and Phil Dolman converted one.
Blackwood battled their way to a 25- home win over Builth Wells and went out of therelgation zone, moving over Fleur de Lys, Carmarthen Athletic and UWIC in the process.
Fly half Jeremy Lloyd led the way with a penalty, drop goal and two conversions and tries came from Jamie Sims (2) and Christian Perry, while Rob Lloyd placed a lone penalty for Builth Wells.
Bonymaen jumped from seveth to fifth place after a 30-0 win over Tonmawr, who now are staring relegation in the face and have eight game to survive, but are already 13 points away from safety.
Scrum half Gareth James, formerly of Penygraig, notched four of the five tries by the Parc Mawr club and wing Chris Griffiths also crossed with Anthony Evans placing a penalty and conversion.
The WRU has teamed up with Crawshay's to tour Georgia in June. The side, which will be called the Crawshays WRU President's XV, will play Emerging Georgia twice, in a tour which supports the Welsh Government's efforts to grow relations between the two countries.
Wales Sevens are looking to re-group after a disappointing tournament last time out in South Africa. The next double leg in New Zealand and Las Vegas offers Gareth Williams a chance to redeem themselves.
Wales Women's head coach Rhys Edwards was at Llandovery to see the conclusion of an entertaining Women's Regional championship where any one of three teams were in contention for title glory on the last day of action.