Full-back Davies picked up a knee injury in the 20-16 defeat to the Blues on Wednesday while Thomas is out of the reckoning with back trouble. The match at the Racecourse Ground in Wrexham will be the Scarlets' third outing in eight days but director of rugby Gareth Jenkins believes his squad will be able to cope.
"We've been able to balance our selection so hopefully we won't be affected too much by the injuries," he said. "We've taken a few casualties and that might pressurise our selection, but we knew this was in front of us and we were quite clear about what this week meant."
Connacht beat the Blues at home in their first game of the season, but will arrive in North Wales on the back of a 34-3 defeat to Edinburgh Gunners.
"They'll be resilient and tough, and will make life really awkward for us," added Jenkins. "They will probably be fresh and they are always capable of tripping sides up."
Despite drawing with Ireland in the opening round of the RBS 6 Nations, Wales defence coach Shaun Edwards believes the championship 'is still in our hands' as he prepares his side to face Scotland at Principality Stadium tomorrow.
Meet the members of the WRU's inaugural Youth Board - after an online selection process which saw a host of high calibre candidates submit video applications the WRU has made its first 15 appointments.The board is made up of individuals aged between 16 and 21, and will meet for the first time at Principality Stadium on Monday 15th February.
The Wales Women's team headed to Dare Valley Country Park on a team bonding exercise as the entire squad got together for the very first time in preparation for this season's Six Nations championship which kicks off on Saturday with a clash against defending champions Ireland, in Donnybrook.