All three of these sides find themselves facing ASDA League Division 1 sides. Merthyr travel to Rodney Parade to meet Newport, Llanharan go to St Helen's to face Swansea and Narberth trek to Sardis Road to tackle Pontypridd.
Another Division 1 v Premiership battle will take place at Caerphilly, where the visitors are Llandovery. It was Llandovery who hit the headlines in the third round by dumping the holders Llanelli out of the competition with a 29-21 home win.
The sole surviving team from North Wales, Division 4 North's Nant Conwy has been rewarded with a home draw against Division 2 East's Rhydyfelin. It will be the fourth straight home tie for the club after victories over Maesteg Quins (32-0), Hirwaun (48-8) and Tylorstown (24-6).
Eight of last weekend's third round games were postponed due to poor weather and those games are due to be played this weekend.
KONICA MINOLTA CUP ROUND 4
(Matches to be played on the weekend of 14 January, 2006)
Abercynon v Glamorgan Wanderers or Ystrad Rhondda
Caerphilly v Llandovery
Builth Wells Cardiff HSOB or Kidwelly
Dunvant v Penclawdd
Ebbw Vale v Aberavon
Maesteg v Carmarthen Quins
Mumbles or Llangennech v Tonna
Nant Conwy v Rhydyfelin
Neath v Bridgend
Newport v Merthyr
New Tredegar or Newport Saracens v UWIC or Llantwit Fardre
Pencoed v Penallta or Bonymaen
Pontypridd v Narberth
Swansea v Llanharan
Tonmawr v Cardiff
Whitland or Bridgend Athletic v Cross Keys or Bedwas