Fiji kicked off their European tour with a 39-29 victory over a New Zealand Divisional XV last Saturday and will have viewed Wales's 41-3 defeat to the All Blacks with interest.
"Wales were pretty bad in the line-outs and its one of the expected weaknesses we are planning to expose," said Fiji manager Simon Poll.
"They were competitive for the first 30 minutes against New Zealand, but slackened down and didn't have any answer for the remainder of the game."
Fiji, who also face Tests in Portugal and Italy this month, are also without Leicester Tigers utility back Seru Rabeni who failed a late fitness test on his knee injury.
Other absent stars include Rupeni Caucaunibuca and Vilimoni Delasau, who are both serving 12-month bans from international rugby.
Agen star Caucau was suspended for failing to join the national team for its matches in June and July, while Canterbury and Crusaders speedster Delasau has been punished for testing positive for cannabis.
Both bans were handed down by the Fiji Rugby Union.
Fiji will share a pool with Wales during Rugby World Cup 2007, so Friday's visit to the Millennium Stadium will offer a taste of what is to come.
Fiji: 15 Norman Ligairi (Secom, Japan), 14 Mosese Luveitasau (Naitasiri), 13 Epeli Ruivadra (World, Japan), 12 Julian Vulakoro (Suva), 11 Sireli Bobo (Biarritz, France), 10 Seremaia Bai (Secom, Japan), 9 Mosese Rauluni (captain, Saracens, England), 8 Aca Ratuva (Agen, France), 7 Sisa Koyamaibole (Taranaki, NZ), 6 Alifereti Doviverata (Yamaha, Japan), 5 Isoa Domolailai (Northland, NZ), 4 Ifereimi Rawaqa (World, Japan), 3 Apisai Nagi (Lautoka), 2 Sunia Koto (Ovalau), 1 Jo Bale (Suva).
Replacements: 16 Bill Gadolo (Suva), 17 Jiko Matawalu (Nadroga), 18 Kele Leawere (Nadroga), 19 Kiniviliame Salabogi (Nadroga), 20 Mosese Volavola (Nadroga), 21 Aporosa Vata (Ovalau), 22 Kameli Ratuvou (Tailevu).