Llanelli go to Llanharan for a Saturday evening game, which on form should go to the men in red, but coach Dennis John will be hoping that his fit, young side can snatch a rare win. A Llanelli victory can bring them level at the top on 42 points. However, Neath are already 24 tries ahead of the Scarlets.
Ebbw Vale will be trying to avoid passive scrums when they entertain Swansea with Jason Williams having last week become the first man to reach 3.000 league points in a career when his 16 against Carmarthen Quins took him to 3,003 while Byron Hayward, his club colleague, has already overhauled Neil Jenkins into second place.
Cross Keys return to action in a derby against Pontypool, while a rejuvenated Newbridge after coach Mike Watkins cracked the whip, travel to meet an Aberavon side that has won six successive matches under new coaches Kevin Hopkins and Mark ones, both former Wales teammates.
Carmarthen Quins, who have lost four of their last five outings, take on Pontypridd, who gained a good 36-22 win over Cardiff last Saturday and Bedwas look for only their second home win of the season as they entertain a slightly off-colour Llandovery.
In the final match, Newport face bottom club Caerphilly at Rodney Parade. Odds are very much on the third-placed Black and Ambers, but it was only a few seasons ago that they lost five successive matches to Caerphilly
Wales Head Coach Rob Howley talks to WRU TV's Sebastian Barrett about the 36-man squad he has just named for the forthcoming Under Armour series, which includes two uncapped players, Ospreys duo Sam Davies and Rory Thornton.
Head coach Rowland Phillips is deligthed he can now call BT Sport Cardiff Arms Park home for his Wales Women's side, who launch their international season next month with games against Scotland and UK Armed Forces in the heart of the capital city.
Wales Sevens star Sam Cross has put his home town club of Brynmawr on the map after winning a silver medal at the Rio Olympics with Team GB. His club have now honoured him by naming their players bar after him, as WRU TV discovered at the official launch, recently.
One of the newest members of the Principality Premiership, Bargoed admit it's proving to be a steep learning curve at the highest level, but are determined to become a force to be reckoned with. WRU TV visited the club last weekend when they took on Llanelli.
Table-topping Aberavon travel to north Wales to tackle RGC 1404 as both teams defend unbeaten starts to the season in the Principality Premiership. WRU TV's Graeme Gillespie visited the Wizards to see how their preparations were going for the game of the weekend.
The Half a Game initiative is currently sweeping across Wales and proving a major success. The scheme aims to give every young player at least half a game every weekend. WRU TV recently visited a festival in Narberth where clubs have fully embraced the initiative.
Both Bargoed and Swansea were seeking their first win of the Principality Premiership season this afternoon. It proved a fruitful day for the hosts - not only did they win, but Bargoed claimed a try bonus point.
Cardiff managed to keep their unbeaten record at home intact, but only just as Bridgend made them work extremely hard before the Blue and Blacks secured a hard fought Principality Premiership win at the BT Sport Arms Park last night.
Former Wales back row Andy Powell gives a guided tour of The Wern, home of Merthyr RFC, who are determined to prove a lot of people wrong and make their mark in their first season in the Principality Premiership.