There will be four matches played in the East and of those, both Monmouth and Chepstow have the chance of claiming the top spot if they gain wins from their home matches against St Peter's and Oakdale respectively. The Trinant-Pontllanfraith match will now be played at Pontllanfraith, while pointless Llanilleth are due to meet Cardiff HSOB.
In the West, the big clash is at Neyland, where Cefneithin are the visitors. If there is not a draw, the winners will join Amman Utd on 18 points. In the other matches, Fishguard take on Milford Haven and Pontarddulais meet Betws.
The only match in the South-East is at Dowlais, where Llandaff North provide the opposition and in the South-West leaders Resolven visit bottom club Pyle, while Aberavon Green Stars meet Glais; Trebanos take on Maesteg Celtic and Ystradgynlais face Morriston.