Ospreys trio Huw Bennett, Andy Lloyd and Luke Tait will all miss the start of the Celtic League campaign against Munster this weekend.
Wales hooker Bennett, who toured Argentina and South Africa in the summer, is suffering a hernia and could also miss the west Wales derby against Llanelli a week later.
Flanker Lloyd is also out for a fortnight with a hamstring problem while coach Lyn Jones is also keeping a close eye on lock Tait's neck strain.
'It's a blow but we have brought in a number of high-quality players to strength in depth to the the squad,' said Jones.
Meanwhile the Ospreys are considering a change in team name and playing colours for next season as they quiz supporters from Neath and Swansea over the future of the regional team.
Ospreys chief executive Andrew Donald said: 'The consultation will be exactly that - a listening exercise. We want to know from supporters what they think we've got right and where we could do better. We'll want to know what they think of the Ospreys' identity and branding, as well as obtain feedback on the Ospreys' future facilities.'
The WRU has teamed up with Crawshay's to tour Georgia in June. The side, which will be called the Crawshays WRU President's XV, will play Emerging Georgia twice, in a tour which supports the Welsh Government's efforts to grow relations between the two countries.
Wales Sevens are looking to re-group after a disappointing tournament last time out in South Africa. The next double leg in New Zealand and Las Vegas offers Gareth Williams a chance to redeem themselves.
Wales Women's head coach Rhys Edwards was at Llandovery to see the conclusion of an entertaining Women's Regional championship where any one of three teams were in contention for title glory on the last day of action.