Ospreys trio Huw Bennett, Andy Lloyd and Luke Tait will all miss the start of the Celtic League campaign against Munster this weekend.
Wales hooker Bennett, who toured Argentina and South Africa in the summer, is suffering a hernia and could also miss the west Wales derby against Llanelli a week later.
Flanker Lloyd is also out for a fortnight with a hamstring problem while coach Lyn Jones is also keeping a close eye on lock Tait's neck strain.
'It's a blow but we have brought in a number of high-quality players to strength in depth to the the squad,' said Jones.
Meanwhile the Ospreys are considering a change in team name and playing colours for next season as they quiz supporters from Neath and Swansea over the future of the regional team.
Ospreys chief executive Andrew Donald said: 'The consultation will be exactly that - a listening exercise. We want to know from supporters what they think we've got right and where we could do better. We'll want to know what they think of the Ospreys' identity and branding, as well as obtain feedback on the Ospreys' future facilities.'
After two years in the international wilderness, Adi Taviner is hoping to make up for lost time when she takes part in her second Women's Rugby World Cup which kicks off in Paris next Friday where Wales take on hosts, France.
The WRU's Women and Girls legacy events - #TRY OUR GAME have proved popular this week with current players and newcomers to the game learning new skills and picking up tips from national squad players.
We caught up with Shona and Ellie from the Wales women team ahead of the start of the Women's Rugby World Cup in Paris next month at a recent women's training session to encourage and promote more women and girls to try their hand at rugby. #tryourgame
The Women's Rugby World Cup warm-up clash between Wales and USA proved bittersweet for centre Elen Evans. Despite being one of the star performers on the day on her 50th Test appearance, USA edged home 10-7 at Cross Keys.
Wales completed their Junior World Championship campaign with a victory over Samoa. Team manager Mark Taylor and No 8 James Benjamin reflect on a tournament which saw Wales win three games and lose two.