Ospreys trio Huw Bennett, Andy Lloyd and Luke Tait will all miss the start of the Celtic League campaign against Munster this weekend.
Wales hooker Bennett, who toured Argentina and South Africa in the summer, is suffering a hernia and could also miss the west Wales derby against Llanelli a week later.
Flanker Lloyd is also out for a fortnight with a hamstring problem while coach Lyn Jones is also keeping a close eye on lock Tait's neck strain.
'It's a blow but we have brought in a number of high-quality players to strength in depth to the the squad,' said Jones.
Meanwhile the Ospreys are considering a change in team name and playing colours for next season as they quiz supporters from Neath and Swansea over the future of the regional team.
Ospreys chief executive Andrew Donald said: 'The consultation will be exactly that - a listening exercise. We want to know from supporters what they think we've got right and where we could do better. We'll want to know what they think of the Ospreys' identity and branding, as well as obtain feedback on the Ospreys' future facilities.'
Carmarthen Quins are holding an exhibition to commemorate club players who fought in World War I. All welcome to the clubhouse on Friday afternoon to learn more about local history, or share any family anecdotes or artifacts.
Defence coach Shaun Edwards believes Saturday's clash against England - the 'form team in world rugby' - poses a huge challenge for his side but he is confident, with Wales beginning to show the defensive qualities displayed in the last two World Cups,