Newport and Neath carry on the fight for the Premier leadership with Newport currently ahead by eight tries and both on 52 points.
Both are favourites to in their league matches with Newport home to Llandovery and Neath travelling to Pontypool Park, having thrashed Pooler just a week ago in the Konica Minolta Cup.
Cardiff travel to Newbridge hoping to continue their improvement, while Llanelli entertain Caerphilly, bottom club Ebbw vale taken Aberavon and Cross
Keys meet Bridgend at Pandy Park. Pontypridd will kick off at 5.30pm against Carmarthen Quins and Swansea take on Bedwas at St Helen's on Sunday afternoon.
Premier Division Fixtures
Cross Keys v Bridgend
Ebbw Vale v Aberavon
Llanelli v Caerphilly
Newbridge v Cardiff
Newport v Llandovery
Pontypool v Neath
Pontypridd v Carmarthen Qns
Swansea v Bedwas
The annual Women's club launch was held at the Wales Centre of Excellence where National Women's Head Coach and Programme Lead Rhys Edwards, Competition Secretary Adrian Howell and Cardiff Met player Ffion Jones express eagerness for the new campaign to get under way.
WRU TV follows Wales' RWC training squad on day one of their camp in North Wales. The squad were greeted to an official welcome in Colwyn Bay and then headed for an afternoon of team building at ZipWorld