Newport and Neath carry on the fight for the Premier leadership with Newport currently ahead by eight tries and both on 52 points.
Both are favourites to in their league matches with Newport home to Llandovery and Neath travelling to Pontypool Park, having thrashed Pooler just a week ago in the Konica Minolta Cup.
Cardiff travel to Newbridge hoping to continue their improvement, while Llanelli entertain Caerphilly, bottom club Ebbw vale taken Aberavon and Cross
Keys meet Bridgend at Pandy Park. Pontypridd will kick off at 5.30pm against Carmarthen Quins and Swansea take on Bedwas at St Helen's on Sunday afternoon.
Premier Division Fixtures
Cross Keys v Bridgend
Ebbw Vale v Aberavon
Llanelli v Caerphilly
Newbridge v Cardiff
Newport v Llandovery
Pontypool v Neath
Pontypridd v Carmarthen Qns
Swansea v Bedwas
Carmarthen Quins are holding an exhibition to commemorate club players who fought in World War I. All welcome to the clubhouse on Friday afternoon to learn more about local history, or share any family anecdotes or artifacts.
Defence coach Shaun Edwards believes Saturday's clash against England - the 'form team in world rugby' - poses a huge challenge for his side but he is confident, with Wales beginning to show the defensive qualities displayed in the last two World Cups,