Division Three Top club Bargoed in the East will travel to bottom club Talywain knowing that they already lead the division by five points and that Abergavenny face a difficult game at Blaina. In the South-East there is probably the top game of the four areas as the unbeaten clubs of Rhydyfelin and Mountain Ash meet up, though the Old Firm will be without a few regulars in their back division. Also in the South-East, Ruthin will provide the interesting opposition for Barry at the Reservoir Field.
Loughor take their unbeaten tag in the West to Penclawdd, while leaders Gorseinon also travel, going to Llandeilo, but the closest game could be between Pembroke Dock Quins and Aberystwyth at the Bierspool Ground.
Brynoch hope to bounce back from defeat by Maesteg Quins as they take on Kenfig Hill in the South-West. The Mules are among six clubs who are just three points behind Banwen, though none of them will meet.
Division Four Resolven, runaway leaders of the South-West, face second-placed Tonna on Vaughan Field with all the other clubs hoping for an away win. Just as important is the game at Fishguard in the West as the fifth-placed Seagulls face leaders Amman United with Neyland, home to Llandybie, and Cefneithin, away to Milford Haven, awaiting the Amman result.
Both unbeaten clubs, Fairwater and Aberdare, in the South-East, would feel confident of gaining victories as The Snakes travel to Dowlais and Fairwater face Cowbridge at Ashcroft Park. An interesting battle will be on the Athletic Field as Penarth entertain Llantwit Major.
North leaders Llangefni face a trip to Parc Bodegroes to take on Pwllheli, but second-placed Colwyn Bay will find Llandudno a difficult task at Maesdu Recereation Ground, while third-placed Mold are at Chester Road against Caernarfon.
The two unbeaten clubs of this division will both be at home as Nantyglo face on second-placed Machen at Banna Park in the East and Pembroke take on Penygroes at Crickmarren Field in the West.
The East will see the meeting of the Cardiff-based Saints with St Joseph's facing St Alban's on Blackweir, while Llanybydder, with nine straight losses, go in hope to end that run at St David's.
While South Wales Police face Bridgend Sports at Waterton Cross, the big match of the South-East is at Cefn Coed's Black Patch, alias Cae Rhodd Evan, where high-flying Porth are the visitors.
Four clubs are on 21 points in the South-West, but none of them meet up as Birchgrove, Crynant and Glyncorrwg are away and Abercrave face Cwmgwrach at Plas y Ddol.
In the North, leaders Bala are at home to Welshpool and Bethesda will be at Dol Dafydd against a useful Llanidloes side.
Wales Head Coach Rob Howley talks to WRU TV's Sebastian Barrett about the 36-man squad he has just named for the forthcoming Under Armour series, which includes two uncapped players, Ospreys duo Sam Davies and Rory Thornton.
Head coach Rowland Phillips is deligthed he can now call BT Sport Cardiff Arms Park home for his Wales Women's side, who launch their international season next month with games against Scotland and UK Armed Forces in the heart of the capital city.
Wales Sevens star Sam Cross has put his home town club of Brynmawr on the map after winning a silver medal at the Rio Olympics with Team GB. His club have now honoured him by naming their players bar after him, as WRU TV discovered at the official launch, recently.
One of the newest members of the Principality Premiership, Bargoed admit it's proving to be a steep learning curve at the highest level, but are determined to become a force to be reckoned with. WRU TV visited the club last weekend when they took on Llanelli.
Table-topping Aberavon travel to north Wales to tackle RGC 1404 as both teams defend unbeaten starts to the season in the Principality Premiership. WRU TV's Graeme Gillespie visited the Wizards to see how their preparations were going for the game of the weekend.
The Half a Game initiative is currently sweeping across Wales and proving a major success. The scheme aims to give every young player at least half a game every weekend. WRU TV recently visited a festival in Narberth where clubs have fully embraced the initiative.
Both Bargoed and Swansea were seeking their first win of the Principality Premiership season this afternoon. It proved a fruitful day for the hosts - not only did they win, but Bargoed claimed a try bonus point.