The match of the season thus far is expected at the Gnoll when unbeaten leaders Neath take on last season's champions, Newport. Having had three points docked and losing at Ebbw Vale last week, Newport will see this as make or break to topple the Welsh All Blacks.
Just as interesting as the top match will be the Aberavon-Llanelli clash as the four-match run of the Wizards will be on the line against the ten-match winning streak of the second -placed Scarlets. Bedwas, without a home win, take on free-scoring Swansea and Ebbw Vale look for another home win as they face the speedy Cardiff back division.
While Cross Keys and Llandovery meet in a mid-table battle, there is a basement struggle at Llanharan where bottom club Caerphilly are the visitors in an important match. Other strongly-contested games will be between Bridgend against Pontypool and Pontypridd at home to Newbridge.
Whenever Bedlinog tackle Penallta a massive fixure is guaranteed but this Sunday there will be even more emphasis placed on the two rivals when they contest the SSE Swalec Plate final at Principality Stadium.
Ahead of their SSE SWALEC Bowl Final clash with Taffs Well at Principality Stadium on Sunday, Burry Port share their #FABXV nomination with WRUTV in the search for Welsh rugby's greatest volunteers. Everyone can get involved by sending nominations via twitter to @WRU_Community using the hashtag #FABXV
Cardiff Blues prop Gethin Jenkins and Ospreys centre Ben John look ahead to the first game at Principality Stadium in Saturday's double header which is promising to be a special occasion for all Welsh fans.
Carmarthen Quins Director of Rugby Ian Jones and committee member Jeff Thomas along with Llandovery chairman Handel Davies look ahead to Sunday's SSE SWALEC Cup showdown where both teams are out to prove 'West is best'
SWALEC ambassador Shane WIlliams is looking forward to Sunday's Finals Day where the Cup, Bowl and Plate offers a great opportunity for players and teams to experience the magic of playing at Principality Stadium
Carmarthen Quins coach Richard Kelly believes it is an exciting time to be part of the Scarlets region as his side take on local rivals Llandovery in the SSE Swalec Cup final on Sunday, as WRU TV's Graeme Gillespie discovers