Last season's Division Four East winners Bargoed have started with a bang and take their unbeaten record to Pontypool United, who also are yet to lose and have Stuart Lawrence back at fly half.
Leaders Rhymney take on Pill Harriers, but the Brewers will be hard to beat at home this season, while in the West there will hotly contested matches at Tenby and Trimsaran, where Gorseinon and Loughor are the visitors.
Match of the day in the South-East is sure to be at Mountain Ash as the Old Firm take on local rivals Gilfach Goch. Both clubs are in a winning vein and looking impressive, though Gilfach are scoring much higher.
Another hard battle is in prospect as Nelson welcome Rhydyfelin and at the other end of the table, Barry go to Pentyrch and Penygraig hope for a rare win against Brecon. In the South-West, Glynneath hope to break their duck against newly-promoted Cwmgors and Alltwen against Nantyffyllon is just as important at the rear end of the table.
Nearly 40 players were involved in the first Wales Under 18 training session of the season. WRU National Performance Manager Gethin Watts is excited at the potential shown by the group and expects the Regional Under 18 Championship to hone their skills even further.