New boys Builth Wells provided a huge shock as they gained a 25-13 win at Narberth with full back Rob Lloyd scoring all 25 points by converting his own try and placing six penalties.
Blackwood could also be pleased in beating Whitland 20-7 and Carmarthen Athletic held off a spirited Fleur de Lys 32-22 with Lee Williams notching 17 points. Divisional favourites Maesteg needed a try from old maestro Allan Bateman to defeat Beddau 26-17 and UWIC's youngsters beat Bonymaen 28-8 at Cyncoed.
Few teams succeed at Brynmawr, but Llangennech achieved it by 17-13 and Glamorgan Wanderers spoilt the first match for Tonmawr in this division as Dan Jones fired over a penalty hat-trick and a drop goal in a 12-0 away win.
In the East, Brynithel pulled off a huge shock with a 7-5 win at Merthyr as Gavin Hayes grabbed a second-half try try and Mike Hurn kicked a winning conversion.
Treorchy fell 14-0 away to Newport Saracens, for whom No 8 Ross Madden scored a clinching try while Tredegar crashed 31-8 at Rumney, who made it a good start for new skipper Paul Niblett and coaches Gafyn Cooper and Danny Wilson. In the West, veteran Paul Morris grabbed a try in Dunvant's 29-13 win at Tondu while former Wales Under-21 wing Ken Morris grabbed a brace as Pencoed beat Cwmavon 33-17. Mumbles gained a surprising 18-17 win at Corus.