Coach Declan Kidney has been boosted by the return of Kieran Lewis after close to a year on the sidelines with a cruciate knee injury.
The former Ireland Under-21 (10 caps) / Ireland Schools (4 caps) star has been named amongst the replacements alongside Ireland internationals Victor Costello and Brian O'Meara.
Kidney has kept faith with the same side that drew 11-11 with Worcester last weekend. Brian O'Riordan is partnered at half-back with David McAllister while Leo Cullen again captains the side.
Kidney has named nine substitutes in total with two vacancies to be confirmed in the coming days.
Cardiff Blues coach Dai Young is yet to name his side, but it is expected hooker Andrew Lewis will be fit to return to action after injuring his jaw against Leicester Tigers last Saturday.
Blues coach Dai Young said: "The end of last year showed how competitive the League is.
"We've strengthened our squad, but so have the other regions in Wales.
"We've got real strength in depth and competition for places, something we've been missing for a few years.
"But there are no easy games in the League, whether the Irish sides play their internationals or not," young told BBC Wales Sport.
LEINSTER15: James Norton 14: John McWeeney 13: Christian Warner 12: David Quinlan11: Gary Brown 10: David McAllister 9: Brian O'Riordan 1: Emmett Byrne 2: Gavin Hickie 3: Peter Coyle 4: Leo Cullen (Captain) 5: Ben Gissing 6: Aidan McCullen 7: Shane Jennings 8: Des Dillon