Leaders Carmarthen Quins are unbeaten after three matches and visit Caerphilly, who have lost all three games, but the division is still far from settled and the Cheesemen are quite capable of causing an upset at Virginia Park.
The big clash must be at the Arms Park, where Cardiff entertain Newport in what could prove a high-scoring match after Newport hung on to their unbeaten tag on Wednesday with a try by former Cardiff forward Darren Davies.
Bottom club Ebbw Vale meet inconsistent Llanelli at Eugene Cross Park and Pontypool, who have gone close without winning, travel to Aberavon, who may have two players named John Jones and two named Paul Morgan in their squad.
Cross Keys historian Horace Jeffries is ready to launch a second book on the history of the club in two weeks time, but before that comes the derby meeting with Newbridge at Pandy Park, while the other three fixtures will see Bridgend against Bedwas at the Brewery Field; Pontypridd meeting Llandovery at Sardis Road and Swansea taking on Llanharan at St Helen's.
Carmarthen Quins are holding an exhibition to commemorate club players who fought in World War I. All welcome to the clubhouse on Friday afternoon to learn more about local history, or share any family anecdotes or artifacts.
Defence coach Shaun Edwards believes Saturday's clash against England - the 'form team in world rugby' - poses a huge challenge for his side but he is confident, with Wales beginning to show the defensive qualities displayed in the last two World Cups,
Women in the Ospreys region recently completed a Level 1 coaching course and are looking forward to putting their theory into practice in clubs and schools across the region. A women only course has been organised for the Scarlets region starting next week, full details at the end of the video.