In the Lloyds TSB Welsh National League Division One, leaders Blackwood take on UWIC, but there will interest at the Oval, when the ailing squads of Treorchy and Tredegar meet up.
Abertillery's Two East match at home to Llantwit Fardre is still in doubt, while Fleur de Lys hope to start their season away to Croesyceiliog and the Penygraig-Dinas Powys match pairs clubs who did not play last Saturday for differing reasons. Two West includes Dunvant's visit to Waunarlwydd that will see the visitors hoping to continue their revival. The Pencoed home game against Bridgend Athletic will see the most easterly of the West division in
Old Illtydians follow Wednesday's match against Glamorgan County with the visit of an in-form Newport HSOB in Three East; Pontyberem v Llandeilo is one from an interesting Three West; Mountain Ash hope to keep up their return to form at home to Treherbert in Three South-East and Ystradgynlais, back on the winning run, have their hands full with visitors Maesteg Quins in Three South West.
St Peters at home to Blaina in Four East will provide some thrills; the Pembroke Dock Quins v Tycroes is off in Four West with a wedding taking place;
Penarth break new ground at Pontycymmer in Four South-East and Cefn Cribbwr will find Cwmgors a handful in Four South-West.
Pointless clubs Blaenavon and St Alban's fight it out in Five East; unbeaten Furnace entertain winless St David's in Five West; South Wales Police will travel to Ferndale in Five South-East and Resolven's comeback continues at home to BP Llandarcy in Five South-West.
North Wales returns to league matches with 22 clubs due to appear, including a first start for Bangor University at Bro Ffestiniog in Division Five, where the highlight could be Welshpool at home to Bethesda.
Division Four North's big match is unquestionably Ruthin v Nant Conwy, where the top two in the division thus far will be meeting.