Coaches Phil John and Alun Harries have selected a much changed line up from the one that finished last season with Tylorstown's Hannah Szigetvari making her debut on the right wing.
Melissa Berry captains the side from the back row where she lines up alongside the experienced Kylie Wilson and another debutant in UWIC's Catrina Nicholas.
Cardiff Quins' Nicola John wins the No 2 shirt in front of last season's Wales U19 hooker Sophie Williams who is on the bench. Non Evans returns from her World XV exploits to resume her Welsh duties in the No 15 shirt.
The opposition feature, amongst others, New Zealand, Canadian and English Internationals and will be a real test for the Welsh this early in the season. They have in their ranks the two most capped players of all time in ex Welsh skipper Liza Burgess and England's Gill Burns who between them possess over 150 caps.
Phil John said "We are privileged to have such opposition here in Wales. They are effectively a female Barbarians team from across the World and it will be an indicator of where and how our off season work has left us. We need to start on a positive note and get the girls playing as they have been training."
1. Catrin Edwards (Cardiff Quins)
2. Nicola John (Cardiff Quins)
3. Kath Lenaghan (Cardiff Quins)
4. Ayla Rose (Llandaff North)
5. Kath Foale (Saracens)
6. Catrina Nicholas (UWIC)
7. Kylie Wilson (Caernarfon)
8. Mel Berry (Worcester) CAPTAIN
9. Cath Walkley (Aberystwyth)
10. Awen Thomas (Cardiff Quins)
11. Hannah Szigetvari (Tylorstown)
12. Rhian Williams (Wasps)
13. Louise Rickard (Sudbury)
14. Hayley Baxter (UWIC)
15. Non Evans (Clifton)
Sophie Williams (Camberley)
Jenny Davies (Cardiff Quins)
Amy Broadstock (Llandaff North)
Becky Dando (UWIC)
Esther Eckley (Llandaff North)
Amy Day (Llandaff North)
Stacey Saunders (Tylorstown)
Elen Evans (Dolgellau)
Lowri Jones (Bala)