Neath-Swansea Ospreys utility Shane Williams is facing a fight to be fit ahead of Wales' final World Cup pool match against New Zealand in Sydney on Sunday.
The Test winger, who can also slot in at scrum-half, was expected to get a run in the eagerly awaited match but is battling the flu.
The news is further bad news for coach Steve Hansen, who lost OspreyS prop Duncan Jones with a fractured fibula during the Italy clash.
Wales won that match 27-15 to secure their place in the World Cup quarter-finals.
Better news for Hansen is that Gareth Thomas, Sonny Parker and Kevin Morgan, who all took knocks in the crucial match against Italy on Saturday, but are all expected to be available for selection this weekend.
Wales have not beaten New Zeland since 1953, but with the All Blacks have been short of competitive matches in this year's cup, giving rise to hope that this could be the hour of success.
Despite drawing with Ireland in the opening round of the RBS 6 Nations, Wales defence coach Shaun Edwards believes the championship 'is still in our hands' as he prepares his side to face Scotland at Principality Stadium tomorrow.
Meet the members of the WRU's inaugural Youth Board - after an online selection process which saw a host of high calibre candidates submit video applications the WRU has made its first 15 appointments.The board is made up of individuals aged between 16 and 21, and will meet for the first time at Principality Stadium on Monday 15th February.
The Wales Women's team headed to Dare Valley Country Park on a team bonding exercise as the entire squad got together for the very first time in preparation for this season's Six Nations championship which kicks off on Saturday with a clash against defending champions Ireland, in Donnybrook.