While leaders Llanharan have a seemingly easy task against Treorchy, there could be problems for Maesteg, who face a stern test at Cyncoed against the students of UWIC. Rumney against Narberth could be the most competitive match however, with the Otters likely to find Riverside Park to their liking.
In Two East, Abertillery are due to meet Penygraig and it remains to be seen if both sides will be at full strength, while Hirwaun face a derby match against Merthyr and new leaders Abercynon make the trip to Ystrad Rhondda, whose full back Dean Jones suffered a double break of the leg last Saturday. Top battle in the West is certainly at Bridgend, where the Athletic meet unbeaten leaders
Corus in what promises to be a thrilling encounter.
Three East leaders Newport HSOB meet Abergavenny, while the top clash could be the All-Newport affair at the Civil Service Ground, where the local Saracens take on Pill Harriers. In the West, Kidwelly versus Tumble and Lampeter against Pontyberem look the pick of the games.
Improving Gilfach Goch face Nantymoel and top club Treherbert at Pentyrch are the highlights of Three South-East, while Three South-West will see unbeaten Bryncoch entertain Mumbles and joint leaders Maesteg Quins travel to Skewen.
Four East will see leaders Bargoed go to injury-hit Caldicot and in-form Blaina take on Chepstow at Central Park. Four West leaders Llandybie go to pointless Tycroes and there are tight matches expected between Llanelli Wanderers v Pembroke Dock Quins and Loughor v Burry Port.
The Abercwmboi v Pontycymmer match stands out in Four South-East while the Fairwater match with Penarth brings together two clubs that lost last week.
Four South-West leaders Cwmgors go to Rhigos and Taibach visit Abercrave. In North Wales, the top clash is at Llangefni where Ruthin are the visitors and at least one 100% record must go! Bottom club Bala hope for their first points at home to Newtown. Those matches are in Division four, while in Five North there are no league fixtures scheduled until November 8.
Bettws take a week out as the bye team in Five East, where Trinant entertain St Alban's and Machen go to Blaenavon. In Five West, leaders Cefneithin entertain St Clears. Five South-East table-toppers Llantwit Major are not in action, though improving South Wales Police take on a revived Rhiwbina, who have won twice this season. Five South-West unbeaten leaders Resolven go to Cwmgwrach
and also unbeaten are Pontardawe, who meet Porthcawl at home.
One occasion to look out or on October 24 will be a centenary dinner at the Rhondda Fach Sports Centre, when former Wales captain, scrum half, coach and president, Clive Rowlands, will be guest of honour of Tylorstown RFC.