(Sat 15 kick-off 2.30pm)
Neath will be playing their second game in four days, having seen off Cardiff 39-24 at the John Smiths Gnoll on Wednesday night. Click here for the match report
The Welsh All Blacks come up against a confident Caerphilly side who's last Premiership outing saw them dispatch current Welsh club champions 33-20 click here for the match report
And Neath coach Lyn Jones is taking the Caerphilly threat seriously.
"Caerphilly have developed a strong game over the last three or four months, and qualifying for the latter rounds of European competition will have given them a lot of confidence," he said.
"In beating Llanelli they showed that us that if we are not 100% going into the game we will suffer.
"We need to show the kind of form and commitment to playing positive expansive rugby that we had in beating Cardiff."
Caerphilly, PARKER PEN SHIELD semi-finalists, will have the services of Llanelli and Wales front rower Martyn Madden - Click here for more on this story