Tom Prydie moves to fullback to replace Dan Evans, whilst Andy Tuilagi and Jonathan Evans return to the starting line up.
Owen Evans makes his first Dragons start after coming on as a try scoring replacement against the Wasps. Steve Jones also rejoins the side after missing last week's away game and the back row then remains the same as the team who played against the London Wasps.
Scrum half half Mike Phillips returns to Wales to take on the Dragons after coming on as a substitute in last week's convincing 71-7 rout of Mogliano.
Dragons Tom Prydie, Will Harries, Adam Hughes, Andy Tuilagi, Tonderai Chavhanga, Lewis Robling, Jonathan Evans, Owen Evans, Steve Jones, Nathan Buck, Ian Nimmo, Rob Sidoli, Tom Brown, Lewis Evans (c), Toby Faletau.
Sam Parry, Nathan Williams, Dan Way, Adam Jones, Jevon Groves, Liam Davies, Steffan Jones, Pat Leach.