There was another local derby at Brewery Field, where Bridgend overcame Bridgend Athletic 31-3. The Ravens' tries came from back row No.8 Tom Morgan, Andrew Waite and replacement No.8 Scott Hicks, while ex Athletic winger Rhys Ward Jones bagged a brace against his former side.
Swansea bounced back from recent league woe to brush past visiting RGC1404 29-12. With first half tries from fullback Nick J Thomas, wing Nathan Brookes and centre Aled Jenkins, The Whites led 22-0 at the break, and with three conversions from Thomas and a further five points from centre Nick Harwood, cruised into the next round.
Carmarthen Quins came away with goods at Narbeth, as the Premiership side scored five tries to win 36-15. Aaron Banfield gave the away side the lead and with a second try under his belt, and two more from Rhodri Wells, the game looked dead and buried at halftime.
Despite a brave fight back after the interval, with a try from Stewart Morris and a penalty try, Narbeth failed to claw back the points and a try from centre Alex Bickersgill sealed the deal for the Quins.
Parc y Scarlets saw two Premiership sides lock horns. A late try from Kyle Evans wasn't enough for Llanelli as Pontypridd's centre Gary Williams went over twice to deny the home team a place in the second round. The final score was 22-14 to Ponty.