In the SWALEC Cup, last year's beaten finalists Pontypridd face a difficult trip to Llanelli in a match that will see one of Welsh rugby's cup giants exit the competition at the first hurdle.
Ponty fell to a surprise defeat against Cross Keys in last season's final at the Millennium Stadium and will have to overcome the ultimate cup kings, 14 times winners Llanelli on their own patch in order to progress to round two.
Elsewhere, rivals Bridgend and Bridgend Athletic clash at Brewery Field with local bragging rights at stake. The Ravens started their Premiership campaign with a win over Llanelli last weekend but the local derby will surely bring out the best in both teams.
In another derby, Cardiff welcome Cardiff Met, formerly UWIC to the Arms Park while Whitland take on Aberavon, Ebbw Vale host fellow Gwent side Newbridge and Llandovery travel to Bedwas in the other all Premiership tie.
North Wales side RGC 1404 will be hoping to win their first ever SWALEC Cup game but they face a difficult tie away to Swansea, while the remaining round one fixtures see Llanharan take on Beddau, Bonymaen visit Newport, Narberth clash with Premiership side Carmarthen and Blackwood host Pontypool.
Defending champions Cross Keys as well as Bargoed, Glamorgan Wanderers, Neath and Tata Steel all have byes in the first round.
The sides involved will have to wait for their cup run to start though with the round one fixtures taking place the weekend of January 26 2013..
The second phase of the Principality Premiership kicked off last week with the introduction of two tiers. In this week's podcast Aberavon No 8 Chris Davies tells WRU TV's Graeme Gillespie he's had to change his game while Cross Keys head coach Greg Woods says his side still have plenty to aim for.
Women in the Ospreys region recently completed a Level 1 coaching course and are looking forward to putting their theory into practice in clubs and schools across the region. A women only course has been organised for the Scarlets region starting next week, full details at the end of the video.
Bedwas may have surprised a few by finishing the first phase of the Principality Premiership in second spot, but head coach Steve Law is confident his side have enough ability to remain competitive in phase two as they travel to Ebbw Vale to kick off their Tier 1 campaign, as WRU TV's Graeme Gillespie, hears.
How do you follow a dancing hippopotamus - the Ospreys wheelchair rugby team has just the 'oneness' to do it say the BBC! For a decade the sight of a herd of hippos synchronised swimming around their own private blue lagoon, has lit up our television screens at regular intervals between favourite BBC One shows. But now the nation's most watched channel has relinquished its famous amphibious mammals in favour of a new show-reel which includes the Ospreys wheelchair rugby team.
Treorchy's award-winning secretary Bryan James, Ebbw Vale's Nigel Davies and all four regions on the Principality Welsh Rugby Union Podcast. We look ahead fo Europe with Rob Evans of the Scarlets, Dan Baker of the Ospreys, Ellis Jenkins of the Blues, as well as Nic Cudd and Tom Prydie of the Dragons.
Martyn Phillips has discussed details of the newly published 'Strategy for Welsh Rugby' which puts in black and white terms the plans and direction of the governing body of the national sport in Wales for the next decade.
Nigel Davies is a relieved man after seeing his side secure the last spot for phase two of this season's Principality Premiership with a hard fought victory against Gwent rivals, Cross Keys at Eugene Cross Park on Saturday.
Bedwas director of rugby Steve Law is looking for a big reaction from his players as they once again host Merthyr at the Bridge Field a week after being dumped out of the WRU National Cup by the Ironmen.
Mathew Nuthall's love affair with major finals at Principality Stadium is on course for a final act after he scored a try in Caerphilly's quarter-final demolition of last season WRU National Bowl runners-up, Taffs Well.
Pontypool beat Llanelli in the last round of the WRU National Cup and the Championship leaders added the scalp of another Principality Premiership side to their collection as they put Cardiff to the sword in the second half to win 43-32 and progress into the last eight.
Carmarthen Quins are holding an exhibition to commemorate club players who fought in World War I. All welcome to the clubhouse on Friday afternoon to learn more about local history, or share any family anecdotes or artifacts.
Developing the game in Wales and creating a stable and progressive environment for players of the future
Taking the grass roots game out across the length and breadth of the nation, the National Leagues are the focus of the community rugby in Wales
The National Cup, Plate and Bowl continue the legacy of the WRU Challenge Cup, culminating in a shot at glory at the Millennium Stadium
Women's Community Rugby embraces both the regional and community club game from Girls' Leagues through to the Women's Premier Division