Neath coach Neil Edwards has made three changes from the side which lost to Llanelli with Liam Davies, Ceri Jones and James Goode all coming into the side. Goode captains the side from lock.
Edwards said: "Both sides suffered home defeats in their opening games so will have something to prove on Sunday.
"We were very disappointed to throw away a 16-6 half time advantage but our performance fell away in the second-half and that is something we can ill afford against anyone.
"We will certainly be looking for the full 80-minutes' worth on Sunday and we have tweaked one or two things this week."
Swansea meanwhile, have the IRB Junior World Player of the year available, Sam Davies starting at fly half. He is joined in the side by Rhodri Hughes, Nicky Smith and Nicky Thomas who all played alongside Davies at the Junior World Championship this summer.
No. 8 Dan Baker, who toured Japan with Wales in June, will clearly be a marked man.
Watch live coverage of Neath against Swansea on S4C from 2.15pm tomorrow.
Neath: 15 Ceri Young 14 Dale Ford 13 Liam Davies 12 David Adam Jones 11 Alec Jenkins 10 David Langdon 9 Joshua Davies, 1 Roy Jones 2 Sion Crocker 3 Ceri Jones 4 Dafydd Jones 5 James Goode (c) 6 Jack William Jones 7 Garyn Daniel 8 Jordan Collier.
Replacements: Christopher Davies, Keiren Mattocks, Jonothan Griffiths, Bowdy Davies, Gareth Mark Bateman, Kyle Tayler, John Leyshon, Marc Jones.
Swansea: 15 Nicky J Thomas 14 Andrew Claypole 13 Aled Jenkins 12 Dai Watts (c) 11 Richard Williams 10 Sam Davies 9 Justin James, 1 Nicky Smith 2 Paul John 3 Nicky Thomas 4 Teghan Price 5 Rhodri Hughes 6 Sam Pailor 7 Rob Dudley Jones 8 Dan Baker.
Replacements: Scott Otten, Toby Hurdle, Tom Sloane, Lyndon Batemen, Matthew Davies, Jake Cole, Paul Davies, Josh Hamer.