| The first round on the 19th January will see Llandaff North at home to League rivals Pontyclun. Aberstywth take on first Division Blaenau Gwent and Brecon travel to Carmarthen Quins.
In the North, Bala face Bangor University and Nant Conwy enter the competition against top of the table Ruthin.
For the complete draw click on 'Domestic rugby' then on 'Seniors'
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